The EDNRB Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to EDNRB, endothelin B receptor, ETB, ETBR, and HSCR. This antibody recognizes Human, Mouse, Rat, Porcine, and Rabbit antigen. The EDNRB Antibody (C-term) has been validated for the following applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene